Discontinuation of statins assessed
نویسندگان
چکیده
منابع مشابه
Discontinuation of statins in routine care settings: a cohort study.
BACKGROUND Systematic data on discontinuation of statins in routine practice of medicine are limited. OBJECTIVE To investigate the reasons for statin discontinuation and the role of statin-related events (clinical events or symptoms believed to have been caused by statins) in routine care settings. DESIGN A retrospective cohort study. SETTING Practices affiliated with Brigham and Women's ...
متن کاملStatins: the high risks of discontinuation and large benefits of continuation
In their mini-review/short communication in this issue of the Archives of Medical Science, Dr. Paraskevas et al. [1] draw proper attention to the consequences of statin discontinuation. They focus primarily on the cerebrovascular disease but their conclusion that absolute benefits of discontinuation are small and the absolute risks are high is consistent with a large and robust totality of evid...
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BACKGROUND Discontinuing medications is a complex decision making process and an important medical practice. It is a tool in reducing polypharmacy, reducing health system expenditure and improving patient quality of life. Few studies have looked at how general practitioners (GPs) discontinue a medication, in agreement with the patients, from a professional perspective. Three research questions ...
متن کاملAssociation of statins and statin discontinuation with poor outcome and survival after intracerebral hemorrhage.
BACKGROUND AND PURPOSE Studies suggest a protective role for statins after intracerebral hemorrhage, but many failed to assess statin discontinuation, did not include postdischarge outcomes, or did not account for withdrawal of care. We studied the relationship between preintracerebral hemorrhage statin use and in-hospital statin discontinuation on stroke severity and 30-day mortality. METHOD...
متن کاملCholesterol suppresses antimicrobial effect of statins
Objective(s):Isoprenoid biosynthesis is a key metabolic pathway to produce a wide variety of biomolecules such as cholesterol and carotenoids, which target cell membranes. On the other hand, it has been reported that statins known as inhibitors of isoprenoid biosynthesis and cholesterol lowering agents, may have a direct antimicrobial effect on the some bacteria. The exact action of statins in ...
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ژورنال
عنوان ژورنال: Nature Reviews Cardiology
سال: 2015
ISSN: 1759-5002,1759-5010
DOI: 10.1038/nrcardio.2015.59